CSA - Comp Stool Analysis with PCR (R)

Description

The Comprehensive Stool Analysis with PCR evaluates the status of beneficial bacteria, imbalanced commensal bacteria, pathogenic bacteria and yeasts. If pathogenic cultures are identified, a sensitivity panel is provided to facilitate the selection of pharmaceutical or natural treatment agents. The efficiency of digestion and absorption is measured via faecal elastase, fat and carbohydrates, whilst the biomarkers of calprotectin, lysozyme, and lactoferrin can be used to assess inflammation. This can help to differentiate inflammation associated with inflammatory bowel disease (IBD) from that noted in irritable bowel syndrome (IBS). Humoral immune status of the gut is measured by secretory IgA (sIgA) while the assessment of short-chain fatty acids reflects overall gut health and microbiome balance. This profile is indicated for gastrointestinal symptoms, autoimmune disease, joint pain, IBD, IBS, inflammation, food sensitivities, nutritional deficiencies and skin conditions.

Methodology

The test is broken down into different sections:
GI Pathogens measured by multiplex PCR.
Culturing of commensal and pathogenic bacteria and yeast
Elastase and Calprotectin - Turbidimetric Immunoassay
Lactoferrin, Lysozyme, sIgA - Elisa
Carbohydrates – Colormetric
Fat Stain – Sudan IV
SCFA – Gas Chromatography
Beta Glucuronidase - Quantitative endpoint enzymatic (RUO)
Occult Blood – Guaiac
Stool pH - ISE

When should I use

This profile is indicated for gastrointestinal symptoms, autoimmune disease, joint pain, IBD, IBS, inflammation, food sensitivities, nutritional deficiencies and skin conditions.
When testing budget is limited, and parasitic infection is not suspected, this provides a lower price point than the GI360.